Peyronie's disease is a significant andrological issue characterized by the formation of hard scar tissue (plaques) that have lost elasticity in the penile sheath, making sexual intercourse difficult or impossible. In classic treatments, drugs injected into the plaque (such as verapamil) may show limited efficacy. SVF therapy in Peyronie's disease is an innovative approach that aims to dissolve and repair the fibrotic structure at the cellular level, thanks to live stem cells and regenerative factors injected directly into the plaque. This method is safely applied to Peyronie's patients in modern andrology clinics.
The Effect of SVF Stem Cells on Plaques
SVF injection alters the structure of abnormal collagen fibers (fibrosis) accumulating in the Peyronie's plaque:
- Collagenase Activation: It stimulates the body's own enzymes (collagenase) to dissolve the hardened collagen bonds within the plaque.
- Inhibition of Fibrosis: It promotes the softening of the plaque by increasing the production of new and flexible collagen fibers (Type 3 collagen).
- Reduction of Curvature: As the plaque softens, the pulling effect during erection decreases, leading to a significant improvement in penile curvature and erection pain.
SVF therapy yields highly successful results, potentially eliminating the need for surgery entirely, especially when applied during the early active phase of the disease.