Sexual Health
July 2, 2026
6 min read

Exosome and New Treatments in Peyronie's Disease (Penile Curvature)

Op. Dr. Fettah Tosun

Op. Dr. Fettah Tosun

Üroloji Uzmanı

Peyronie's disease is a condition in which the elastic sheath of the penis calcifies, forming hard plaques that result in painful curvature of the penis during erection. If left untreated in the early stages, it can lead to permanent deformities and erectile dysfunction.

What is Exosome and Regenerative Therapy?

Exosomes, which are derived from stem cells and contain growth factors and intercellular signaling molecules, have revolutionized Peyronie's treatment in recent years. Exosome injection applied to the plaque area dissolves the hardened fibrosis and allows the tissue to stretch again.

Other Alternatives in Peyronie's Treatment

  • ESWT (Shockwave Therapy): Facilitates the breaking down of plaques, reduces pain, and increases vascularization.
  • Intralesional Injections: Helps to stop plaque growth in the early active phase.
  • Surgical Correction: The definitive solution preferred for advanced curvatures in stable patients.
  • In our clinic, we achieve successful results without surgery in patients presenting early-stage Peyronie's disease, thanks to regenerative therapies (exosome, ESWT).

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